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DMSO Penetrate skin so easily. Beacause, DMSO catalyzes a change from the normal beta sheet form to a more alpha-helical one. This conformational change creates holes in the keratin matrix that allows DMSO and molecules dissolved in DMSO to penetrate the skin.

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Description:
Dimethyl sulfoxide (DMSO; (CH 3) 2 SO) is a polar aprotic solvent with a highly polar S O group and two hydrophobic CH 3 groups.

Abstract. The penetration mechanism of dimethyl sulfoxide (DMSO) in human skinin vivoand in vitro and pig ear skin in vitro was studied using attenuated total reflectance (ATR) Fourier transform (FT) infrared (IR) and near-FT-Raman spectroscopy.

Views: 36188 Date: 31.08.2019 Favorited:1
Category: Penetration

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